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Cytotec or Misoprostol stimulates increased secretion of the protective mucus that lines the gastrointestinal tract and increases mucosal blood flow, thereby increasing mucosal integrity. with Diclofenac in Arthrotec). Misoprostol is commonly prescribed offlabel to cause birth induction by uterine contractions and the ripening (effacement or thinning) of the cervix. Misoprostol is highly effective and much less expensive than pitocin and dinoprostone, the FDAapproved drugs for medically necessary labor induction. Trial metaanalysis by the Cochrane Collaboration demonstrates no difference in efficacy or side effects between inductions undertaken with dinoprostone or misoprostol (when used at the correct dosage). Concern has been expressed about the overuse or misuse of misoprostol for labor induction. High doses can cause uterine rupture (especially in women who have previously had a caesarean section), fetal death and severe fetal brain damage, according to a CBS Evening News story by correspondent Sharyn Alfonsi.[1] All induction agents cause uterine contractions this can affect the blood supply to the fetus, especially if contractions become very frequent. Induction agents therefore need to be used with great care and with close fetal monitoring. One of the problems with induction using prostaglandins (either cervidil or misoprostol) is that once given, the process is difficult to reverse. Tiffany Co Infinity Ring